Karma Takapa graduated from the Film and Television Institute of India, Pune, specializing in Direction and Screenplay writing. He co-directed the Chhattisgarhi language feature ‘Mor Mann Ke Bharam’ (An Illusion of my mind, 2015) that premiered at the 17th Mumbai Film Festival, 2015 winning the Special Jury Prize. 

His debut film as a director, Ralang Road (2017), premiered in the main competition at 52nd Karlovy Vary International Film Festival and went on to several festivals around the globe. His earlier films include a series of short fiction and documentary films, experimenting with narrative forms and exploring spaces, including his hometown in the state of Sikkim. 

His next film, Upar Neeche, starring Sayani Gupta and Shubham is currently in Post Production.

He recently portrayed the lead character of Dev in the Amazon Prime series, The Last Hour, directed by Amit Kumar.